We occasionally use this ratio to estimate the degree of hydration of a patient. 4. BUN/Creatinine Ratio - The BUN/Creatinine ratio is useful in the differential diagnosis of acute or chronic renal disease. Reduced renal perfusion, e.g., congestive heart failure, or recent onset of urinary tract obstruction will result in an increase in BUN/Creatinine ratio. The BUN/Creatinine ratio is useful in the differential diagnosis of acute or chronic renal disease. Outside the United States, particularly in Canada and Europe, the term urea is often used. Normal BUN is 10 to 20 mg/100 mL and serum creatinine is 0.6 to 1.2 mg/100 mL. 2. In medicine, the BUN-to-creatinine ratio is the ratio of two serum laboratory values, the blood urea nitrogen (BUN) (mg/dL) and serum creatinine (Cr) (mg/dL). When the ratio approaches 20:1, it suggests a problem with blood flow to the kidney; this may be caused by conditions such as heart failure or dehydration. A high BUN to creatinine ratio is mostly associated with the following symptoms: Frequent urination Bone and Joint Pains Itching and Swelling (in the extremities) Poor Appetite Fatigue Discolored urine Muscle Cramping Nausea and Vomiting Donate Your Car Before The End of The Year For a Tax Benefit Before that, it is essential to go through both tests. 3. Reference range for the two parameters is summarized below: Urea is a waste product of protein metabolization, formed in the liver and serves to measure state of … BUN and serum creatinine are best interpreted together, comparing the two results. Please Note: If results for BUN and Creatinine are both within the normal reference range, the BUN/Creatinine ratio will not be reported (not applicable). 6. Renal failure (acute or chronic) produces a BUN to serum creatinine ratio of 10:1. Low BUN and Creatinine Ratio: Understanding Your Test Result BUN Test. The bun creatinine ratio is a comparison between the concentration of two substances in the blood: creatinine and blood urea nitrogen (or BUN). Bun/creatinine ratio of 25 bun was 23 creatinine,serum 0.93 bun/creatinine ratio of 25 bun was 23 creatinine,serum 0.93 on 06/2012 on 6/2011 ratio was 12 bun was 12 creatinine … A normal BUN-to-creatinine ratio is 15:1, according to "Renal Pathophysiology." for more about ARF (acute renal failure) differential diagnosis. An extrarenal problem produces a BUN to serum creatinine ratio of greater than 25:1. See also for more about ARF (acute renal failure) differential diagnosis. What does BUN-creatinine ratio 26 mean? BUN/Cr (S) ratio > 20 (fraction) indicates prerenal causes. BUN/Cr (S) ratio 10 (fraction) indicates renal causes. 5. Distinguishing features include a bland urine sediment ,3 a urine osmolality of greater than 500 mOsm and a BUN–to–serum creatinine ratio of greater than 20:1 . Clinical Significance: The BUN/Creatinine ratio is useful in the differential diagnosis of acute or chronic renal disease.Reduced renal perfusion, e.g. Increased urea formation also results in an increase in the ratio, e.g., gastrointestinal bleeding, trauma, etc. The BUN to creatinine ratio is a calculated ratio that does not mean anything in regards to kidney disease. First off is the BUN test that evaluates the amount of... Creatinine Test. This is a diagnostic test that can tell a physician much about the health of the kidneys. You should not be concerned. BUN Creatinine Ratio = BUN / Creatinine BUN and creatinine are measured in serum, usually in mg/dL. Reduced renal perfusion, e.g., congestive heart failure, or recent onset of urinary tract obstruction will result in an increase in BUN/Creatinine ratio.